Diabetes insipidus (DI) is a rare endocrine disease involving antidiuretic hormone (ADH), encompassing both central and nephrogenic causes.Inability to respond to or produce ADH leads to inability of the kidneys to reabsorb water, resulting in hypotonic polyuria and, if lack of hydration, hypernatremia.DI cannot be cured and is an unfamiliar diseas

Cisplatin resistance in head and neck squamous cell carcinoma (HNSCC) reduces survival.In this study we hypothesized that methylation of key genes mediates cisplatin resistance.We determined whether a demethylating drug, decitabine, could augment the anti-proliferative and apoptotic effects of cisplatin on SCC-25/CP, a cisplatin-resistant tongue SC

Purpose: Binocular traumatic or atraumatic iris defects can lead to an increased sensitivity to glare and cosmetic disfigurement.Surgical iris reconstruction is one approach to alleviate these problems.We report the clinical outcomes after medically indicated bilateral implantation of an Artificial Iris prosthesis in three patients with binocular i